N-acetyl Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment ACTH(4-7), modified with an N-terminal acetyl group and a C-terminal Pro-Gly-Pro extension. This structural adaptation enhances its stability against enzymatic degradation. N-acetyl Semax interacts with melanocortin receptors (MC₄ and MC₅), modulating pathways linked to cognitive function, stress response, and neuroprotection.
N-Acetyl Semax Amidate Product Description
N-Acetyl Semax Amidate is a stabilized synthetic peptide variant engineered through N-terminal acetylation and C-terminal amidation to resist enzymatic degradation and extend biological activity. This modification replaces the original peptide’s terminal carboxylic acid (-COOH) with an amide group (-NH₂), enhancing its stability.
Structurally defined as Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂, it demonstrates prolonged half-life (~30 minutes longer than standard Semax) and increased neuroprotective efficacy, modulating neurotransmitters like serotonin and dopamine and upregulating BDNF expression. Preclinical studies highlight its potential in cognitive enhancement, neuroregeneration, and therapeutic applications for stroke or neurodegenerative disorders. This compound is intended for in-vitro research and laboratory use only. Not for human consumption.
Every batch is independently third-party tested using HPLC purity analysis and mass spectrometry. We guarantee ≥99% purity on all our research peptides, with a full Certificate of Analysis provided for each lot.
Orders placed before 12PM Pacific Time ship same-day, Monday–Friday. You'll receive a tracking number via email once your order leaves our facility. All orders are shipped with discreet packaging.
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